The Vitamin B12 Group of Factors

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Detection of vitamin B12 deficiency in older people by measuring vitamin B12 or the active fraction of vitamin B12, holotranscobalamin.

BACKGROUND Impaired vitamin B(12) function and decreased vitamin B(12) status have been associated with neurological and cognitive impairment. Current assays analyze total vitamin B(12) concentration, only a small percentage of which is metabolically active. Concentrations of this active component, carried on holotranscobalamin (holoTC), may be of greater relevance than total vitamin B(12). M...

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Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency.

BACKGROUND Vitamin B12 deficiency is common, and the incidence increases with age. Most people with vitamin B12 deficiency are treated in primary care with intramuscular (IM) vitamin B12. Doctors may not be prescribing oral vitamin B12 formulations because they may be unaware of this option or have concerns regarding its effectiveness. OBJECTIVES To assess the effects of oral vitamin B12 vers...

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Paper chromatography of vitamin B12 and related bacterial growth factors.

In a preliminary note (l), the present authors reported that Lactobacillus Eeichmannii 313 is capable of using six alternative factors for growth in vitamin Bn-deficient media. Two of these were found in vitamin Blz concentrates and presumably represent two forms of the vitamin. Hoffmann et al. (2) previously noted that crystalline antipernicious anemia factor (APA) (vitamin B1.J supports the g...

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AB156. Homocysteine and vitamin B12: risk factors for erectile dysfunction

Transl Androl Urol, Vol 3, Suppl 1 September 2014 www.amepc.org/tau © Translational Andrology and Urology. All rights reserved. followed up in 2013. ED was estimated by the score of the five-item international index of erectile dysfunction (IIEF-5). TT, SHBG, E2, FSH, LH were gauged with precise instrument. FT, BT were calculated by Vermeulen’s formula. Results: A total of 651 Chinese healthy m...

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Vitamin B12 Deficiency

Functional vitamin B12 deficiency is a syndrome where a wide variety of symptoms in the presence of “normal” serum levels of the vitamin respond to vitamin B12 therapy. A series of patients with functional vitamin B12 deficiency are described whose presenting features were drenching night sweats and fatigue. Reliance on serum vitamin B12 levels as a diagnostic test would have obscured the cause...

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ژورنال

عنوان ژورنال: BMJ

سال: 1951

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.4699.151